发布时间:2020-04-17 10:47:33 浏览量:10221

苏建忠,研究员,博士生导师
温州市健康大数据与转化医学重点实验室主任
温眼视光学院、附属眼视光医院和生物医学工程学院
国家高层海外青年人才,浙江省高校领军人才,温州市第17届杰出青年。主持国家自然科学“面上项目、国家科技部重点研发子项目、国家自然科学重点基金子项目”,浙江省“杰出青年、领雁计划”等科研课题10余项,累计经费2000余万元。开发在线算法工具和数据库11个,发表高水平SCI论文80余篇,其中以通讯作者(含共同)在Science Translational Medicine、 Nature Microbiology、Nature Communications、Blood、Cell Reports、Cancer Cell、Genome Biology、Genome Medicine、PNAS、Ophthalmology、Nucleic Acids Research和IOVS等国际高水平期刊发表研究论文30余篇,H指数42,获省部级科研奖项2项,授权发明专利10项。担任中国生物信息与系统生物学重大疾病组学专委会副主任委员,中康促眼科专委会副主任委员,浙江省生物信息学会副理事长,浙江省生物信息学会健康医学和转化医学委员会主任委员,中华预防医学会生物信息学委员,CCF生物信息专委会委员等职。
个人网站:www.su-lab.org。电子邮箱:sujz@wmu.edu.cn。
研究方向
1)AI视觉健康研究
2)复杂眼病遗传诊断和干预治疗研究
3)视网膜再生修复的表观调控机制和治疗靶点研究
近期代表性研究论文(*共同一作,#共同通信)
1.Liu L*,..., Su J#. Identification and characterization of human retinal stem cells capable of retinal regeneration. Science Translational Medicine, 2025, In Press(中科院一区, 封面)
2. Li J*,.., Su J#. Linking Microbial Genetic Signals and Single-Cell Transcriptomics to Unravel Host-microbe Interactions across Human Tissues, Nature Microbiology, 2025, In Press(中科院一区)
3. Yuan J*,..., Su J#. Exome-wide Association Study Identifies KDELR3 Mutations in Extreme Myopia. Nature Communications, 2024,(中科院一区)
4. Dai W,..., Su J*. RIP-AV: Joint Representative Instance Pre-training with Context Aware Network for Retinal Artery/Vein Segmentation. Medical Image Computing and Computer Assisted Intervention, 2024, (国际视觉人工智能顶级会议论文)
5. Ma Y*,... , Su J#. Polygenic regression uncovers trait-relevant cellular contexts through pathway activation transformation of single-cell RNA sequencing data. Cell Genomics, 2023,(中科院一区)
6. Yu X*,..., Su J#; Myopia Associated Genetics and Intervention Consortiums. Whole-Exome Sequencing Among School-Aged Children With High Myopia. JAMA Network Open, 2023,(中科院一区)
7. Su J*#, ...,Qu J#. Sequencing of 19,219 exomes identifies a low-frequency variant in FKBP5 promoter predisposing to high myopia in a Han Chinese population. Cell Reports, 2023,(中科院一区)
8. Ma Y*,..., Su J#. Integrating single cell sequencing data with GWAS summary statistics reveals genetics-influenced CD16+ monocytes and memory CD8+T cells involved in severe COVID-19. Genome Medicine, 2022,(中科院一区)
9. Yu F*,..., Su J#: CFEA: a cell-free epigenome atlas in human diseases. Nucleic Acids Research 2020,(中科院一区)
10. Zhang X*#,..., Su J#, Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis. Blood 2020. (中科院一区,封面)