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张子城

发布时间:2020-05-16 00:00:49 浏览量:1239

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张子城,硕士研究生

本科毕业于哈尔滨医科大学生物技术专业。 

现从事基于NGS大数据的肿瘤学与免疫学的交叉研究,试图揭示和解析复杂的肿瘤免疫微环境,为癌症的免疫治疗提供新的标记物和治疗靶点。 

研究生期间荣获学院学术擂台赛一等奖,研究生卓越奖学金一次。

目前,共发表SCI研究论文11篇,其中以第一作者和并列第一作者发表SCI论文7篇(一区top期刊3篇),累计影响因子110点。


主要研究论文

PUBLICATION(# equally contribution and * corresponding author)

1、Wang G#, Xu D#, Zhang Z#, Li X, Shi J, Sun J, Liu HZ, Li X*, Zhou M* & Zheng T*. The pan-cancer landscape of crosstalk between epithelial-mesenchymal transition and immune evasion relevant to prognosis and immunotherapy response. npj Precision Oncology, 2021, 5(1):56.

2、Y. Yu#, Z. Zhang#, Q. Meng, Y. Ma, X. Fan, J. Sun. Comparison of the Efficacy of S-1 Plus Oxaliplatin or Capecitabine Plus Oxaliplatin for Six and Eight Chemotherapy Cycles as Adjuvant Chemotherapy in Patients With Stage II-III Gastric Cancer After D2 Resection. Front Oncol. 2021, 24(11): 684627.

3、Zhang Z#, Yan C#, Li K, Bao S, Li L, Chen L, Zhao J, Sun J* & Zhou M*. Pan-cancer characterization of lncRNA modifiers of immune microenvironment reveals clinically distinct de novo tumor subtypes. npj Genomic Medicine, 2021, 6(1):52.

4、Zhao HQ#, Gu SS#, Bao SQ, Yan CC, Zhang ZC, Hou P, Zhou M*, Sun J*. Mechanistically-derived patient-level framework for precision medicine identifies a personalized immune prognostic signature in high-grade serous ovarian cancer. Briefings in Bioinformatics, 2021, 22(3): bbaa069

5、Zhou M#Zhang ZC#, Bao SQ#, Hou P, Yan CC, Su J*, Sun J*. Computational recognition of lncRNA signature of tumor-infiltrating B lymphocytes with potential implications in prognosis and immunotherapy of bladder cancer. Briefings in Bioinformatics, 2021, 22(3): bbaa047

6、Zhang ZC#, Bao SQ#, Yan CC, Hou P, Zhou M*, Sun J*. Computational principles and practice for decoding immune contexture in the tumor microenvironment. Briefings in Bioinformatics, 2021, 22(3): bbaa075

7、Sun J# Zhang Z#Bao S#, Yan C, Hou P, Wu N, Su J, Xu L* and Zhou M*. Identification of tumor immune infiltration-associated lncRNAs for improving prognosis and immunotherapy response of patients with non-small cell lung cancer. Journal for ImmunoTherapy of Cancer. 2020, 8(1).

8、Chen X#, Zhang Z#, Wang X#, Zhao H, Li M, Ma Y, Ji Y, Zhang C, Wu K, Xiang L, Sun L, Zhou M* and Jin Z*. The circular RNome of developmental retina in mice. Molecular Therapy-Nucleic Acids. 2020, 19: 339-349.

9、Bao S, Zhao H, Yuan J, Fan D, Zhang Z, Su J* and Zhou M*. Computational identification of mutator-derived lncRNA signatures of genome instability for improving the clinical outcome of cancers: a case study in breast cancer. Briefings in bioinformatics, 2020, 21(5):1742-1755 (ESI Highly Cited Paper)

10、Yan C, Zhang Z, Bao S, Hou P, Zhou M, Xu C and Sun J. Computational methods and applications for identifying disease-associated lncRNAs as potential biomarkers and therapeutic targets. Mol Ther Nucleic Acids. 2020, 21:156-171

11、Zhou M, Hu L, Zhang Z, Wu N, Sun J and Su J. Recurrence-Associated Long Non-coding RNA Signature for Determining the Risk of Recurrence in Patients with Colon Cancer. Mol Ther Nucleic Acids. 2018, 12:518-529

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