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闫聪聪

发布时间:2020-05-15 23:58:51 浏览量:1278

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闫聪聪,硕士研究生

本科毕业于哈尔滨医科大学生物医学工程专业。 

研究生期间荣获研究生卓越奖学金一次,学业奖学金一等奖。

现从事基于整合单细胞及群体细胞多组学数据的卵巢癌免疫分型研究,探究免疫微环境的异质性与病人预后和免疫治疗或化学治疗应答的关系,为卵巢癌病人的治疗提供新的生物标记物和治疗靶点。

目前,共发表SCI研究论文7篇,其中以第一作者和并列第一作者发表SCI文章论文2篇,累计影响因子60点。



学习和研究经历

1、2019.09-至今,温州医科大学, 眼视光学院、附属眼视光医院和生物医学工程学院,硕士研究生

2、2015.09-2019.07,哈尔滨医科大学, 生物信息科学与技术学院

 

主要研究论文

PUBLICATION(# equally contribution and * corresponding author)

1、Yan C, Zhang Z, Bao S, Hou P, Zhou M, Xu C, et al. Computational Methods and Applications for Identifying Disease-Associated lncRNAs as Potential Biomarkers and Therapeutic Targets. Molecular Therapy - Nucleic Acids. 2020;21(September):156-71.

2、Zhang Z#, Yan C#, Li K, Bao S, Li L, Chen L, Zhao J, Sun J* & Zhou M*. Pan-cancer characterization of lncRNA modifiers of immune microenvironment reveals clinically distinct de novo tumor subtypes. npj Genomic Medicine, 2021, 6(1):52. 

3、Zhao HQ#, Gu SS#, Bao SQ, Yan CC, Zhang ZZ, Hou P, Zhou M*, Sun J*. Mechanistically-derived patient-level framework for precision medicine identifies a personalized immune prognostic signature in high-grade serous ovarian cancer. Briefings in Bioinformatics, 2021, 22(3): bbaa069

4、Zhou M#,Zhang ZC#, Bao SQ#, Hou P, Yan CC, Su J*, Sun J*. Computational recognition of lncRNA signature of tumor-infiltrating B lymphocytes with potential implications in prognosis and immunotherapy of bladder cancer. Briefings in Bioinformatics, 2021, 22(3): bbaa047

5、Zhang ZC#, Bao SQ#, Yan CC, Hou P, Zhou M#, Sun J*. Computational principles and practice for decoding immune contexture in the tumor microenvironment. Briefings in Bioinformatics, 2021, 22(3): bbaa075

6、Hou P#, Bao SQ#, Fan DD#Yan CC, Su J*, Qu J*, Zhou M*. Machine learning-based integrative analysis of methylome and transcriptome identifies novel prognostic DNA methylation signature in uveal melanoma. Briefings in Bioinformatics, 2021,22(4): bbaa371

7、Sun J#, Zhang Z#, Bao S#Yan C, Hou P, Wu N, Su J, Xu L* and Zhou M*. Identification of tumor immune infiltration-associated lncRNAs for improving prognosis and immunotherapy response of patients with non-small cell lung cancer. Journal for ImmunoTherapy of Cancer. 2020, 8(1).


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